Hello, has an e collar been tried? Get one big enough so the dog can't get at the paws. How about rinsing her paws off after going outside using the puppy wipes with aloe vera? What about cleaning solutions used around the house. I had to switch to all natural products. What about epsom salts soaks? That stuff has done wonders for my dog, but be careful about drying. I just stick my dog in the tub pour in half a bag and soak for fifteen minutes. Is the dog getting enough exercise, sometimes can be a behavior issue. Good luck.